David Crabb is Professor of Statistics and Vision Research in the School of Health Science at City, University of London. He gained degrees in Mathematics and Statistics at Oxford and Sheffield before completing a PhD in Visual Science in 1996. Following a post-doctoral position at University College London and a lectureship in Nottingham, he took up his position at City in 2005. Professor Crabb is a fellow of the Royal Statistical Society and Honorary Consultant in Visual Science at Moorfields Eye Hospital. Professor Crabb’s research laboratory (Twitter:: @crabblab), contains a lively mixture of vision scientists, optometrists, psychologists, mathematicians and computer scientists. This research laboratory focuses on measurement in vision especially visual fields, imaging and eye movements. The laboratory has attracted an international reputation, especially in glaucoma research. One of the main themes of Professor Crabb’s work is relating the different stages in the process of chronic eye disease to patient’s visual disability and everyday life. Other themes include ocular imaging and image processing, the design of new tests for visual disorders and using ‘big data’ extracted from eye clinics to assess health service delivery of age-related eye disease.
AMD: What Matters to the Patient
Successful clinical management of age related eye disease should equate to correct decisions about intensifying treatment, of initiating intervention, when patients are at risk of developing ‘visual disability’. Moreover, the benchmark for a new treatment success in a clinical trial should really be aligned to measureable changes that affect patient’s everyday life rather than imperceptible changes on a clinical chart. Yet little is known about what visual loss, at different stages of age-related macular degeneration (AMD), specifically affect patients’ abilities to perform everyday visual tasks. Being able to link the measurements taken in the clinic to at least an estimate of what patients visually ‘can’ and ‘cannot do’ would be enormously helpful. The first part of this presentation will showcase some of the work published in this area by our research laboratory in London illustrating, for example, the difficulties that patients have with search, face recognition and mobility; this includes direct interviews with patients about their main concerns. And what does AMD look like? The second part of this talk will present results from a study highlighting the issue that ‘reconstructions’ of the visual symptoms of AMD, typically developed for patient information and disease awareness programs, are very wrong.
Website Twitter: @crabblab